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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163f269625fe72deefb66620851bce0a6a02bc68a90e4f316047366206c7151a' 
  AND token = 'P65eJf9bYZHVnC4ZsMoZsWbXIz3ON29PqEsJnFkvdAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}