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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '169dc01952f6e001f337d7b8a04065286a21abfea44e1fe7c4f458d44a682d4d' 
  AND token = 'U4FZrPEi6c2DVUkvsmWwxrusBp1mD6X+7AHTPiBSrwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}