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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a6424cdb4cb6e936ac1a85c2320e4c2decc084f3299147673120b3476cf645' 
  AND token = '1Q07iX+chfnoiJoYUGj3x+FU1JnuaEvSRSoqbhK2NGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}