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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b49e82f886df4aa1aba89eca087bbfc8335a6fa68c3c57927d8909e3a34cf38' 
  AND token = 'NEoizJ3taWZebEIbv7idbhXRJd5BPJiDH1SxqKLgqc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}