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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa52b5eadbffe3d892b53525af5dfcf91a17cce57384d7dc7b024ac6fd3c362' 
  AND token = 'ADxzN3kScr0YXdpurLG3Gvrc4bLrfhkfUFAB7BQHTnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}