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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a153ad5d886dc51aa48ad0b0b4cde0e5e554c07b0239aa33309e379eb675bdfe' 
  AND token = '1wthi0JArj3ZiCtn3FYjkx7wc8e18IS0Mas53D40vpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}