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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4665b9fcba4f1e46794d415de6552c3c53784186360b18e91cf24b95163b8051' 
  AND token = 'YxmmE4EV9Mq1sopSOnhR+aW/507YOfFDQ4MmApZUSgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}