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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051e27f31c34469cef69fae475d73c2a15228fc55ee20cb82f4d54c704d99d90' 
  AND token = 'vb4h9ngXUrV9hV3CyxCUcrmD4qM52gkT8OaBNulGQL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}