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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59fe781b753bef5747ffcca4511247180633ce546909d347fcf2e27635b5f20d' 
  AND token = 'hY3zgvuj2zkX8s/G/ylBk6zOeOi212TSIjx5Hzy6bxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}