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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e059a789f90b9b6721e49a7d96332d914db0e083adba4bb7b7819e882da7b55d' 
  AND token = 'JgStTy4Q8QFI9s46NNO5qORGb1BR4W0kkFR+1EVlXT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}