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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708734cc163c6413a37b33af41f60da13c2faba0d53044d66c8c0a88a0145d53' 
  AND token = '0C+GpBY/4rNayVIQD3QjEdj5Rmyc2B2RMYivF0zur+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}