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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '552120825e444f289ea8fd6bebc8d231e1ea25b4ee7652638c0389e3806bfca5' 
  AND token = 'cNGDDnMj5CZZURl9E8Hs7EZDKHyAHOk4b5aQ568ymIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}