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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1007a933a2ada7638dec6f218af919b37facdc8963e12228efb3078e15e4ae50' 
  AND token = 'S+vpfaAXY9Y7Lb04SmxNcQdUmb2n69NXb1DaxunX0ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}