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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2065f76627c2baec89b29a96b663b5ce4b589c66ddaef0d898961d40dc2dace1' 
  AND token = '+ZsQyEaMNwoi7pGLAujDSdg9AdlsxGFeCIljPiA+7jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}