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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea00b82c9bfa68553418e06a974324304ce357e768923a01efae4b37b8145851' 
  AND token = 'we1t8og7a4A+hNvLZBXxD+JcKU1lOkC7kWG4pqoWA3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}