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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc6a165bbb467c6f0d51550023ae7839bda54c8dd9028232e5db7562936d6cf7' 
  AND token = 'adz/YtvNQKpeb9doRiAxEZ4qDGbgjcJ2ZN/eIwypKbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}