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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af7f56f93246d40a8aa8aedaf10ff367294964754fb9ee183f16eafd5ced4a8' 
  AND token = 'PiDzhb8QHkK/DeQXzYErrgmWyaEdr8PDalwUd45IroM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}