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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '325b738a267eacb48705e74927a62112b4ed8a489513e5f2856b5ccd3a544517' 
  AND token = 'WweQLfibKvzFqZs4yOu0OhWA2nz25YrwEtLqQBfW3LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}