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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '279857863d25654b66fac296d054a9d5a6ae2e8a7ed3e61060c5961cd3c4f340' 
  AND token = '483/RuwYzNLK0xZSjshOw/4ZHKnI26ry58tH2Nui1WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}