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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e964519291c02a22c092e22b97387a9af924689779b8fed47a7e61b073089f67' 
  AND token = '19RNrX/IONkafltW/sBfShBZmpZri+4MuN2RaTwAh/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}