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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a4e30b17dca3a0891e5be350778d9b166e93cc097ddcaaeb18bff148b1ad28' 
  AND token = '27nquv8ACq+hYP1oH+q+vXZUIoXGcvBFIhXRsH+Lse8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}