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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781ffa51498f22ae2578087c63a9063a92045dac2280de5b2c9043c825a63243' 
  AND token = '+VvCkGjY1RmDyF0HpiqitoK1G4y5oCEO5Qye2Z66xOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}