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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bb3a862bf5ac330e1c18c432f278ad8e203a76b7944270fbf1dc83c941d2239' 
  AND token = '1u+YNSWiCJRhCnRcaVaIve4g/V4JnJ+MY62Ja1Sg6wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}