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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe4acfc44e65f551e4cd85fb6857ed090c28163fe2665031af775ff472c2a59c' 
  AND token = '1W1DhVKPjCO9cS6YEZ6mqxh8Mq4+GSPb9hD9lWtU4OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}