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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a374f8d6c0045484b9e18403f058296079991dfaed35fd82ec3d7e6d24b5f745' 
  AND token = 'DnFe+9KaxDwI0IYBS3ijQdqF9uZMdyoh+P1DEJdKvM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}