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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f6138a8b71eedabfdd12c216e86ae5c525d4a2bd6ca49f165217345d8bc6574' 
  AND token = 'rO8F4IG9w6WReIVOyfJEeeasQcJQc4NC9BaCtvIDN3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}