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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83303baaa5829023726c5a797dbe3c8db0330dae6b7fa25f9d2a0946d9eec923' 
  AND token = 'cNEy9Qd+v1hE4TT3EVPy7tYVDSJhWcYs4UmQVUhGR2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}