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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ff4489c9730ed20a87c9ffda78934bf41f900a89df895a9946bae6987f9e4c' 
  AND token = 'Le75wnh1PN43McV5JvTQxcFpfg/ap3zNal8NO3YaDt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}