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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6a9ada401e9a6653686f5dcce1f8c3ba6b2b74db9608dc021b592f159747305' 
  AND token = 'LwDIb9tGOK8JbnTD/gfGNOMxF1eyZDG4d4Xj0/zagAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}