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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f83160dcc50a6f06912e69a15035249e776c1a3f184b006cde1f93df45bd77e5' 
  AND token = 'bp5M17R0XvbZQz0MeIK5zjTEqZd+RucRfhvnNqiTx+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}