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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '251fe4196f0cbaff0c9e38f94552a474ad7f9969048e4c9145ac01de20736722' 
  AND token = 'SvWFAwJYNXzxkcez5OhfR715B8tG+cqDY2JBQE0JtdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}