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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ba2da1cc4b974b850be51ad094e9b9c70accc9b877b516fb3d005f5d87d4b78' 
  AND token = 'P/Wqf3tcL+NrxUTHm3UfiGbAUgQ7IkBrIB++AMhKsPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}