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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e91efed5869f7a33400065db55a76baf7083e3d291a1c5d3a6d060fc83d4cf0' 
  AND token = 'mxCAVYvoaTqSclwVo7ouj15OnSny4MY+2LzkUpv6gTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}