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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b59b07fe2beaf9900b0a54a5ab3d9a9afc422d37900c724165c610fdbc1758d' 
  AND token = 'Bn/1+vsvWN634tdYgUWVl3wof3OjN38eaWC+XnToeZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}