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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb3488f713ce3d7f15c30d1847f6dcaa2666b2e2a13f89ba178189a779401ca' 
  AND token = 'neQtNRASp6+U27z991v4AYt3qiBObc6GKLP0XUDjbfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}