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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffb169460e063fb209361911e4c321b9ae53338b466c490e0ccd53667b81b7e6' 
  AND token = 'ZL8a572QSRIyr5wJqQelgZsf2aikBaWB3oQN3LP0c2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}