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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '091448f9e3b1ac4a0fa6122f506535b25c34c971b74f18cf7645810b2f3838b5' 
  AND token = 'cuO6LvqAfM+hHZpk1z5x73KxV/RAZuZZpdcV3dSh8EQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}