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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07070820f43069a639506d9043f212a3d52d5272790f42e6652ecc40a83c5654' 
  AND token = 'MkEmIq/WebB1bxd3xmbaTRiMJQ6Ug+bIte0gylsmSak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}