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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dafa50d030388dbe78c8fb01e12e54f2a00269f1f7e4c48cb82c1c6c430c733b' 
  AND token = 'gvrTx8oVJJ+c64S5m8uLczxFXal2DJjfZ8apDhW3XEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}