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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6410d7d4e103a78f7df462c2b39b17a453bdbb5fa46e763651112c61c7893046' 
  AND token = '1g/BD6X55BWbtzRlvOG4a4GzVWp5aAgCqPO2U/KGqbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}