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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb51f20b004d0a8f1b99c4185a9f545dd65315770680fd28e0a72a5c4e331e6e' 
  AND token = 'Udmk2FDNMX/+bwz94IYZJoc0Cu3tLW1SNFsrhtEHcl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}