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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a9dfd6080f31dd3ba24793cd653841d7d95ed631db3655d78301378a5d56d2e' 
  AND token = 'kguRri52up2FurxIm820dU6a0tt/R3BaILcLO0AJHNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}