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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1918e66c6e18d55c940d32ea1cfa09764748178ceeb8b067af24a444802bc16' 
  AND token = 'RIRQBmicSNYHSlD2KUGvzEO3qLOsx4NL/s4GDk0O1oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}