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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14d4b17973b4b5ab97146dda312be2e88880aee48b874f686b8c1798be66fc53' 
  AND token = 'C6vV49BqsT5msyrggjtQxdRM6jz9gdA/M7+E5qgs8zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}