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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8837bf3ff3934cb51405045ece387cb32da5f5abe1c1adfb880d6b79ad126bd' 
  AND token = 'MEret11PQ4+JaC7dVeNN4OxQV9qNLfZAaEUHWKkDc9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}