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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f77730a1227c9d009325b9f554901f25dd99963dbbc630dd57351b541b8d319f' 
  AND token = 'vz4O3qCs5BKnYVEbq21dMDa01Jvn/vPzTrOvd2cVR2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}