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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17ed339f1478d058c3bb215144f5dae2cdc38cd3cc8752c6fc95ddc788e7c483' 
  AND token = 'Aap+rovHZSLlMRd+boM5v2Y7TXjDwvbaG28E2vExIDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}