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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b5b0368ec8f0af728b803cbd7a1ca7b1bb5bb8c2591a94932d2a0a491ed351e' 
  AND token = 'atta6guAp0ymcNn78mAZi1w1gp0DwSTUQFgxwvAkNCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}