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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '593e73f4b2cf24791a9a4f5d24a4f03cd1d7c3b03381141d8f1fb60e30fa2790' 
  AND token = 'tmU8jJOKET4ZhOTHeTz4HuWt8BxOSRoNoyJ4ig5CtxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}