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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74599d45622f6d3649f2cd72863ccd91adff45b6ea70cfa3ca5863dffbb7ff5e' 
  AND token = 'nhG6uWQclR6MrAdvnihqkl9N5DMhTgCTY7uR/ETv3P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}